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Aimmune Therapeutics posits tentative peanut allergy answer

Carol Ostrow | Aug 15, 2017
t Aimmune’s investigational therapy targets an immune cell subset called TH2A cells — potentially desensitizing patients to the peanut allergy.

A trial treatment for peanut allergy has attracted attention in the media, with a recent Washington state publication highlighting California-based Aimmune Therapeutics Inc.’s “AR101” as a potential immunotherapy with the ability to impact allergen-specific T cells. Read More »

Biothera Pharmaceuticals begins patient dosing for cancer study

American Pharmacy News Reports | Aug 11, 2017
The trial brings together a promising combination approach that may increase patient responses to Keytruda.

Biothera Pharmaceuticals Inc. recently announced that the patient dosing has begun in a Phase 1b/2 clinical study at the Big Ten Cancer Research Consortium to evaluate Biothera’s Imprime PGG in combination with the Merck anti-PD-1 therapy, Keytruda (pembrolizumab), in second-line non-small cell lung cancer. Read More »

Cidara Therapeutics publishes data from study of echinocandin as IAC treatment

American Pharmacy News Reports | Aug 11, 2017
Cidara undertook the study in part because of the current treatments’ 40 percent failure rate.

Cidara Therapeutics Inc., a biotechnology company with a focus on developing anti-infective immunotherapies, recently published data from a study analyzing its next-generation echinocandin agent as a comparison to the treatment for intra-abdominal candidiasis. Read More »

Novartis reports positive 5-year efficacy data from Cosentyx study

American Pharmacy News Reports | Aug 11, 2017
Cosentyx works by specifically inhibiting the IL-17A cytokine that plays a role in driving inflammation.

Novartis, an immunology and dermatology company, recently reported positive five-year efficacy and safety results for Cosentyx after completing a Phase III long-term extension study in patients with moderate-to-severe plaque psoriasis. Read More »

Spectrum Pharmaceuticals completes enrollment for Rolontis study

American Pharmacy News Reports | Aug 10, 2017
CEO Rajesh Shrotriya said the drug can change the company’s growth timeline.

Spectrum Pharmaceuticals Inc., a biotechnology company focusing on hematology and oncology, recently completed enrollment for its Rolontis Phase 3 Advance pivotal study. Read More »

Pfizer's Avastin biosimilar meets primary endpoint in study

American Pharmacy News Reports | Aug 4, 2017
PF-06439535, which Pfizer is developing as a potential biosimilar to Avastin, met its primary objective.

Pfizer Inc. recently announced positive results for its Reflections B7391003 study, which evaluated the safety and efficacy of PF-06439535 as compared to Avastin (bevacizumab). Read More »

Thermo Fisher adds mini implant line to its drug implant development line

American Pharmacy News Reports | Aug 3, 2017
Pharmaceutical manufacturers are seeking fast, reliable solutions for continuous production of novel drug delivery systems.

Thermo Fisher Scientific Inc. recently announced the availability of a fully integrated solution for polymer-based drug implant development and production using hot melt extrusion (HME). Read More »

Merck launches Renflexis as biosimilar with FDA consent

American Pharmacy News Reports | Aug 3, 2017
Renflexis is a tumor necrosis factor (TNF) blocker and is indicated for the treatment of several digestive and autoimmune disorders.

New Jersey-based Merck recently introduced Renflexis (infliximab-abda) in the United States as a biosimilar of Remicade (infliximab) following its FDA approval last April for all eligible indications. Read More »

Good Neighbor Pharmacy network adds fee estimator tool

American Pharmacy News Reports | Jul 30, 2017
AmerisourceBergen strives to simplify industry challenges for independent pharmacists via its Good Neighbor Pharmacy initiative.

Pharmaceutical provider AmerisourceBergen recently unveiled the DIR Fee Estimator, its newest tool in conjunction with its nationwide Good Neighbor Pharmacy network, to streamline transactions between provider networks and pharmacy benefit managers by providing cost estimate ranges. Read More »

Amgen and UCB release positive results for Evenity study

American Pharmacy News Reports | Jul 28, 2017
Patients given Evenity for 12 months followed by alendronate saw reductions in vertebral fracture incidents.

Amgen and UCB recently announced that their Evenity study, which analyzed the drug as a treatment for postmenopausal women with osteoporosis, met both primary endpoints and the secondary endpoint. Read More »

Xynomic Pharma teams with UCSF for PAX Study

American Pharmacy News Reports | Jul 28, 2017
The study will use data from Xynomic Pharma’s Phase 1b study, which was sponsored by the National Cancer Institute.

Xynomic Pharma's has initiated a strategic partnership with the University of California San Francisco for a PAX Study – a multi-national, multi-center, randomized Phase 2/3 study of Pazopanib plus Abexinostat, as opposed to Pazopanib monotherapy in patients with locally advanced or metastatic renal cell carcinoma. Read More »

EMD Serono showcases 14 presentations at CMSC's annual meeting

American Pharmacy News Reports | Jul 26, 2017
The data shows Cladribine reduces annualized relapse rate in patients compared to placebo.

EMD Serono, the biopharmaceutical business of Merck KGaA in the United States and Canada, recently showcased 14 presentations at the 31st Annual Meeting of the Consortium of Multiple Sclerosis Centers, including eight sets of data on Cladribine Tablet, a treatment for patients with relapsing multiple sclerosis. Read More »

Alere launches rapid urine drug screen

American Pharmacy News Reports | Jul 26, 2017
The Alere iCup RX can detect five drugs in a urine sample in five minutes.

Test detects five most commonly misused and abused prescription drugs; five-minute results will facilitate rapid interventions in prescription drug abuse. Read More »

RedHill Biopharma completes BEKINDA Phase II study

American Pharmacy News Reports | Jul 26, 2017
The primary endpoint is the stool consistency response and pain.

The last patient in the Phase II BEKINDA (RBH-102) study has completed the treatment and follow-up, RedHill Biopharma Ltd. announced on Monday. Read More »

PrescribeCare cloud pharmacy service enters North Carolina

American Pharmacy News Reports | Jul 25, 2017
Hundreds of Community Care of North Carolina customers will have access to PrescribeWellness services.

Shifting from a “pill-centric to patient-centric” focus, cloud-based prescription service is now available for North Carolina consumers — enabling streamlined information sharing and care coordination — provider PrescribeWellness announced recently from its hub in Irvine, California. Read More »

Phase 3 trial shows Imbruvica benefits leukemia patients

American Pharmacy News Reports | Jul 21, 2017
Study results show continued survival rates in patients with chronic lymphocytic leukemia for up to four years.

AbbVie recently announced positive follow-up results for its pivotal Phase 3 Resonate trial, which evaluated Imbruvica as a treatment for patients with relapsed/refractory (R/R) chronic lymphocytic leukemia/small lymphocytic leukemia (CLL/SLL). Read More »

Amgen releases positive results for Xgeva Phase 3 study

American Pharmacy News Reports | Jul 21, 2017
Patients treated with Xgeva had fewer renal adverse events compared to those treated with zoledronic acid.

Amgen's Xgeva Phase 3 study, the largest international multiple myeloma trial ever conducted, met its primary endpoint by demonstrating that the drug is non-inferior to zoledronic acid in delaying the time to first on-study skeletal-related event in patients with multiple myeloma. Read More »

Amgen reports primary endpoint success for Phase 2 study

American Pharmacy News Reports | Jul 21, 2017
The combination more than doubled objective response rate in patients with unresectable Stage IIIB-IV melanoma.

Amgen's Phase 2 study evaluating Imlygic combined with Yervoy as a treatment for patients with unresectable Stage IIIB-IV met its​ primary endpoint. Read More »

Sanofi, Regeneron release positive results for carcinoma inhibitor

American Pharmacy News Reports | Jul 19, 2017
REGN2810 is also being evaluated in a Phase 2 study.

Sanofi and Regeneron Pharmaceuticals Inc. recently announced positive results for a Phase 1 study evaluating investigational REGN2810, a checkpoint inhibitor targeting PD-1 (programmed death 1) in patients with advanced cutaneous squamous cell carcinoma. Read More »

Elsevier’s ‘Hive’ 2017 to feature biotech, pharma startups

American Pharmacy News Reports | Jul 19, 2017
Pre-revenue biotech, pharma and other small companies involved in early stage research with at least 10 scientists on staff are eligible.

Specialists at information analytics company Elsevier recently announced that its 2017 season for “The Hive,” its source for rising biotech and pharmaceutical companies, is gearing up with unlimited nomination spots now open for aspiring entrants. Read More »

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